ENDOTOXIN ALTERS DEXTROSE INSULIN SECRETION IN SUCKLING RATS

Glucose and insulin dynamics associated with continuous infusion of dextrose or dextrose and insulin in healthy and endotoxin-exposed horses

Endogenous gut-derived bacterial endotoxin tonically primes pancreatic secretion of insulin in normal rats.

This laboratory has proposed that endogenous gut-derived bacterial endotoxin primes the pancreatic secretion of insulin in normal rats. Endogenous lipopolysaccharide (LPS) is continually absorbed from the gut into intestinal capillaries, and low-grade portal venous endotoxemia is the status quo. Under physiologic conditions, Kupffer cells of the liver totally phagocytize and degrade endotoxin f...

suspension culture alters insulin secretion in induced human umbilical cord matrix-derived mesenchymal cells

objective: worldwide, diabetes mellitus (dm) is an ever-increasing metabolic disorder. a promising approach to the treatment of dm is the implantation of insulin producing cells (ipc) that have been derived from various stem cells. culture conditions play a pivotal role in the quality and quantity of the differentiated cells. in this experimental study, we have applied various culture condition...

Experience during suckling alters later spatial learning.

These experiments explore the role of preweaning experience in learning during the juvenile period. Pups that had been reared with many nipples available reached criterion on an 8-arm radial maze in a few trials; conversely, pups reared with only a few nipples required 3 times the number of trials to reach criterion (Experiment 1). Pups that had been reared with relatively few nipples available...

alpha-Lactalbumin hydrolysate stimulates glucagon-like peptide-2 secretion and small intestinal growth in suckling rats.

We investigated whether bovine milk constituents influenced glucagon-like peptide (GLP)-2 secretion and intestinal growth in suckling rats. Male Sprague-Dawley rats (14 d old) received i.g. infusions of a milk protein fraction, a lactose solution, or the cream fraction of milk. The serum concentration of GLP-2, but not GLP-1, markedly increased in rats administered milk protein compared with th...